thrombasthenia lietuviškai

Paaiškinimas anglų kalba

• a rare autosomal recessive disease in which the platelets do not produce clots in the normal way and hemorrhage results
• A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).