mifepristone lietuviškai

Paaiškinimas anglų kalba

• A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
• an abortion-inducing drug (trade name RU_486) developed in France; when taken during the first five weeks of pregnancy it blocks the action of progesterone so that the uterus sloughs off the embryo