lovastatin lietuviškai

Paaiškinimas anglų kalba

• an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate
• A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.