didanosine lietuviškai
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didanosine tarimas /dɪˈdanəʊsiːn/
didanosine vertimas
- didanozinas
Paaiškinimas anglų kalba
- A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
- an antiviral drug used to combat HIV infection
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